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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCOLN1
All Species:
30.61
Human Site:
Y540
Identified Species:
74.81
UniProt:
Q9GZU1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZU1
NP_065394.1
580
65022
Y540
E
E
S
E
L
Q
A
Y
I
A
Q
C
Q
D
S
Chimpanzee
Pan troglodytes
XP_001152356
580
64990
Y540
E
D
S
E
L
Q
A
Y
I
A
Q
C
Q
D
S
Rhesus Macaque
Macaca mulatta
XP_001089857
580
65086
Y540
E
E
S
E
L
Q
A
Y
I
A
Q
C
Q
D
S
Dog
Lupus familis
XP_854284
577
64733
Y537
E
E
S
E
L
Q
A
Y
I
A
Q
C
Q
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99J21
580
65487
Y540
E
K
S
E
L
Q
A
Y
I
E
Q
C
Q
D
S
Rat
Rattus norvegicus
NP_001099373
580
65461
Y540
E
K
S
E
L
Q
A
Y
I
E
Q
C
Q
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520737
451
50656
E412
E
T
I
K
H
Q
C
E
G
E
A
Q
V
S
Q
Chicken
Gallus gallus
XP_423829
489
56157
Y449
P
V
S
Q
L
H
A
Y
I
A
E
C
K
D
S
Frog
Xenopus laevis
NP_001085687
566
64862
Y525
N
D
N
A
L
Y
Q
Y
I
A
E
C
K
D
S
Zebra Danio
Brachydanio rerio
XP_001336199
565
63585
T525
Y
D
T
I
T
Q
Q
T
Q
D
V
P
Q
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.4
94.4
N.A.
91.3
91.9
N.A.
62.9
60.5
62.4
58.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.7
96.5
N.A.
94.4
95
N.A.
68.7
70.8
76.3
73.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
86.6
86.6
N.A.
13.3
60
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
80
73.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
70
0
0
60
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
80
0
0
0
% C
% Asp:
0
30
0
0
0
0
0
0
0
10
0
0
0
80
0
% D
% Glu:
70
30
0
60
0
0
0
10
0
30
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
80
0
0
0
0
0
0
% I
% Lys:
0
20
0
10
0
0
0
0
0
0
0
0
20
0
0
% K
% Leu:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
10
0
80
20
0
10
0
60
10
70
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
70
0
0
0
0
0
0
0
0
0
0
10
90
% S
% Thr:
0
10
10
0
10
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _